Posted 23 April 2025.
Researchers at the Hudson Institute of Medical Research made significant strides towards a simpler and faster diagnosis of endometriosis, a condition affecting one in seven women. This breakthrough could have revolutionized the way endometriosis is diagnosed, moving away from invasive surgical methods to a non-invasive approach.
Led by Professor Caroline Gargett, the research team focused on the use of menstrual fluid to detect endometriosis. Dr. Shanti Gurung, a key member of the team, published a promising study in the Journal of Extracellular Vesicles. The study explored the potential of small extracellular vesicles (EVs) found in menstrual fluid as biomarkers for endometriosis.
“Extracellular vesicles are nano-sized parcels that cells secrete to communicate with other cells,” explained Dr. Gurung. “Our research identified dysfunctional cellular communication in EVs from women with endometriosis, which could be pivotal for early detection of the disease.”
Endometriosis, as common as asthma or diabetes, often went undiagnosed for years, causing severe pain, fertility issues, and significant impacts on quality of life. In Australia alone, the condition affected around one million people, with an annual cost of $21,000 per individual due to productivity loss.
Dr. Gurung emphasized the broader implications of this research. “A non-invasive diagnostic test could save time, money, and alleviate the pain and discomfort experienced by thousands of individuals,” she said. “Early detection and treatment are crucial for improving the lives of those affected by endometriosis.”
The research team’s efforts were a significant milestone towards better, more accessible healthcare solutions for endometriosis sufferers.
