Principal Scientist – Science & Biotechnology | Research & Development

Posted: 19 May 2022

  • Biotech
  • Drug Discovery & Development
  • New leadership role
Our Client
Our client a precision oncology company developing targeted small molecule therapies for cancer patient populations with no currently effective treatments. They have one clinical-stage program that is out-licensed and four early drug discovery programs that are all potential first in class opportunities.The Opportunity
Our client is seeking a new leader to join their management team.  Working closely with the CEO & Board, you will assist to develop and implement the Company’s research and development strategy. Ideally you have established and advanced small molecule drug discovery campaigns from hit identification through to pre-clinical candidate selection in the pharma/biotechnology sectors.

The Ideal Candidate

  • Work closely with the Company’s research partners integrating target discovery, functional validation and protein engineering/structural biology within a distributed medicinal chemistry environment.
  • Assess hit/lead compounds (e.g., analysis of structure-activity relationship and druglike properties) and coordinate medicinal chemistry and biological activities to support compound progression through the drug development pipeline.
  • Provide strategic and scientific leadership for the Company’s research and development program.
  • Significant prior experience working in a virtual distributed model of drug discovery and development utilising a network of CROs and consultants as needed.

Position Requirements

  • PhD in Organic Chemistry or equivalent, with 5+ years of industry experience, specialising in the discovery and development of novel small-molecule drugs.
  • Experience in devising hit discovery campaigns, lead identification and optimisation development plans and target candidate profiles.
  • Solid understanding and application of pharmacology (PK/PD, ADME) and toxicology activities to support lead optimisation and exploratory preclinical development.
  • Preferred experience in an industry – academic collaborations, working in industry and/or participating in industry sponsored clinical trials an advantage.
  • Oncology experience an advantage.

Our Offer
On offer is a salary package with designed to recognise your qualifications, experience and achievements. Job title to be adjusted commensurate with experience. If you are interested in joining our client in this exciting new challenge, please call Marilyn Jones on 1300 0 MEXEC for a confidential discussion and/or email your résumé with your cover letter to

mexec delivers executive recruitment solutions to the pharmaceutical, biotechnology and broader technology industries. mexec comprises of highly talented and knowledgeable industry experienced Consultants that partner with leading organisations to grow their leadership teams.

We recruit at all levels including senior management, and we are currently recruiting for a variety of opportunities in the area of Sales & Marketing, Management, Medical, Regulatory Affairs, Clinical Research, Pharmacovigilance and Operations. Contact us today.


News & opinion

Member Directory